Stendra avanafil : This is an as-needed medication taken 30 minutes before sex and can last up to six hours. Those with a history of blood pressure or heart issues, hormonal imbalances, mental health issues, and diabetes should consult their doctor before trying PDE5 inhibitors. Your doctor or other health care professional can recommend one for you based on these factors, other health conditions you have and any other medicines you take. They’re often the first line of treatment for trouble getting or keeping an erection, called erectile dysfunction ED. You can take this medicine with or without food 30 minutes before sex, depending on the dose. Most erectile dysfunction medications belong to the drug class known as PDE5 inhibitors , which help relax the muscles and increase blood flow to allow for a full erection.Oral medicines for ED usually work well and cause few side effects. The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil . Get a Savings Card Sign up for a Savings Card and, if eligible, you may save 50% on up to 12 prescriptions of brand-name VIAGRA per year.* * Terms and conditions apply. Check . According to price-comparison site , generic Revatio will cost you as little as $ per pill, depending on where you fill your prescription. That’s compared with .