This will increase the supply of blood to the lungs and reduce the workload of the heart. Comparison with actions of other PDE5 inhibitors[ edit ] Sildenafil and vardenafil inhibit PDE6, an enzyme found in the eye, more than tadalafil. Dosing Guidelines Typical Cialis dosages will differ depending on the conditions it’s prescribed to treat as well as other factors. Can Cialis be used with other treatments for impotence? Tadalafil was approved in in the United States for the treatment of pulmonary arterial hypertension [28] and is under regulatory review in other regions for this condition.Cialis and its generic equivalent tadalafil are very effective in treating men with impotence who have difficulty obtaining and maintaining hard erections. It is also helpful in men who have urinary problems due to an enlarged prostate. Cialis works well for more than 85 percent of men. It is effective for men who have erection problems related. Cialis is a prescription drug used to treat erectile dysfunction and benign prostatic hyperplasia. Learn how to lower long-term drug costs and more. We have good news for you: generic Cialis, used to treat erectile dysfunction (ED)and enlarged prostates, just hit pharmacies. Prices for the generic, known as tadalafil, are more than 50% less than those of brand-name Cialis. As more men are able to afford tadalafil and treat their ED, it’s likely that many will have questions.