Do not take more or less of it or take it more often than prescribed by your doctor. Ask your pharmacist if you have any questions about the type of vardenafil you were given. Side effects Side effects of oral ED medicines are often mild. A newer form of the medicine that dissolves on the tongue might work faster than the pill that you swallow. Do not break, crush, or chew it. If you are taking the rapidly disintegrating tablets, your doctor will not be able to adjust your dose because the rapidly disintegrating tablets are only available in one strength.Vardenafil can typically work to help an erection occur and last longer for anywhere between. In one study, people who took vardenafil reported that it worked for up to after taking a dose. If your erection lasts for longer than . Vardenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, vardenafil works by increasing blood flow to the penis. Vardenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Vardenafil does not cure erectile dysfunction or .